Tri-Mix is a custom-blended intracavernosal injectable combining three potent, complementary vasodilators: Alprostadil (PGE1), Papaverine, and Phentolamine. Designed for patients who do not respond to or tolerate oral PDE5 inhibitors, Tri-Mix works directly on penile smooth muscle tissue. By relaxing arterial smooth muscle and inhibiting sympathetic vasoconstriction, it increases local blood flow to produce a rapid, reliable response independent of systemic neurological signaling.Â
Key Benefits & Patient Experience
Direct Local Vasodilation: Relaxes cavernous smooth muscle and dilates penile arteries for a targeted vascular response without systemic blood pressure side effects.
Rapid Onset & Reliability: Works locally within 5 to 15 minutes of administration, offering predictable performance regardless of oral treatment resistance.
Customizable Compounded Formulations: Strengths and ratios can be precisely adjusted by the prescribing provider to match individual physiological needs and target duration.
Bypasses GI & Liver Metabolism: Direct local administration avoids gastrointestinal degradation, liver first-pass metabolism, and interactions with systemic medications.
US-Compounded Quality: Formulated, sterile-filtered, and batch-tested domestically in our licensed US compounding pharmacy to adhere to strict purity, sterility, and potency standards.
Formulation & Availability
Format: Precision-blended sterile multi-dose vial formulated for intracavernosal administration (kept refrigerated or frozen prior to use as directed).
Administration: Prescribed and shipped directly to your door with sterile injection supplies and detailed guidance following a comprehensive evaluation and instruction by a licensed healthcare provider.